Punch-Out!! wins this category simply through ignorance. While everyone was up in arms about Modern Warfare 2's "No Russian" level, Punch-Out!! successfully got away with being offensive to almost every culture out there. The Indian fighter wears a turban and invokes mystical powers, the Japanese fighter expels sushi when hit, and the Russian character is named Vodka Drunkenski in the Japanese version (he drinks soda in the U.S. version). Let me repeat that: The Russian fighter's name is Vodka Drunkenski.

And no, being an equal-opportunity offender doesn't make it right. It just makes your game that much more insensitive of other cultures, Nintendo.

Runners-Up: Modern Warfare 2 , Resident Evil 5