"Amy and Evan covered the topic of violence in Uncharted extensively in a 1up interview:
"...you almost have to take the gameplay as a metaphor. Maybe that's going to sound like a cop-out, but, we want the game to be fun at the end of the day. It's not to be taken seriously."
http://www.1up.com/do/feature?cId=3175544
Also, in the moment when Drake pulls the museum guard off the roof, if you watch closely, the guard comes up to the surface of the water and swims away.
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"...you almost have to take the gameplay as a metaphor. Maybe that's going to sound like a cop-out, but, we want the game to be fun at the end of the day. It's not to be taken seriously."
http://www.1up.com/do/feature?cId=3175544
Also, in the moment when Drake pulls the museum guard off the roof, if you watch closely, the guard comes up to the surface of the water and swims away.
"